MEDICAL TREATMENT OF TOXIC GOITER IN AN AREA OF IODINE DEFICIENCY

medical treatment of toxic goiter in an area of iodine deficiency

the response to methimazole [1-methyl-2-mercapto-imidazole (mmi)] therapy, 10 mg twice daily in 15 patients and propylthiouracil (p tu) therapy, 100mg twice daily in 10 patients with diffuse toxic goiter was evaluated in an area of iodine deficiency (tehran). the mean free t4 index (ft4i) decreased from 22.7± 6.8 (± sd) to 10.8± 2.8 in mmi-treated, and from 25.1± 6.8 to 13.2± 2.1 in ptu-treated...

EFFECT OF IODINE DEFICIENCY ON I.Q.LEVELS OF APPARENTLY NORMAL INHABITANTS OF AN ENDEMIC GOITER AREA

Effect of Iodine Deficiency on IQ of Apparently- Normal School Children of an Area of Endemic Goiter

SUMMARY Different degrees of neurological and psychological problems are observed in endemic goiter inhabitants. To determine the effect of iodine deficiency on IQ, we checked the IQ and size of the thyroid of 194 students of an endemic goiter area and compared with that of 224 students of a non-endemic goiter area in Kohkiloyeh & Boyer Ahmad province. The average IQ of students in endemic goi...

Comparison of Two Propylthiouracil Preparations in Treatment of Toxic Goiter

In order to compare the effect of propylthiouracil (PTU) of Iran Hormone Co. and that of Dr. Herbrand KG, Germany, 28 patients with toxic goiter entered this study. Each patient received 200 mg PTU daily for the first 4 weeks and 50 mg daily thereafter. 17 patients received PTU from Iran Hormone (group 1) and 111 took PTU from Germany (group 2). T4, T3 and TSH by RIA and resine T3, uptake were ...

effect of iodine deficiency on i.q.levels of apparently normal inhabitants of an endemic goiter area

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UpToDate®: 'Treatment of toxic adenoma and toxic multinodular goiter'

There are two clinical situations in which establishing the diagnosis of a toxic adenoma or toxic multinodular goiter is more difficult. First, the autonomously functioning tissue may be sufficiently diffuse that it is difficult to differentiate a toxic multinodular goiter from Graves' disease by thyroid scintigraphy alone. When it is important to distinguish these disorders, a high serum conce...